Class Notes: 

ONLINE CLASS LECTURES: When possible I will prepare online lectures. If your schedule or "other" circumstances require that you miss class the lectures are there for you. These are 10 - 20 min long and can be watched using the wimba website.

You will ALSO need to watch two guided exploration movies in chapter 21 on this book website.

FOR THE Biochemistry of Cancer, I have found a Free Online version of The Cell A Molecular Approach Geoffrey Cooper.  Chapter 15
Don't forget the handouts on Cancer as well.  Your book also has some info on cancer (chapter 13&22). Click here to get to the Chapter on Cancer for a more detailed info on the Biochemistry of Cancer.

Logging On to Wimba - Click on the desired lecture link in the table below. If you have not used Wimba on the computer before RUN THE WIZARD! Then click on the participant login button. The room ID is CHEM410JosephProvost .Use any name you wish. There you will see the ppt lectures, my voice and some notes written on the ppt as I give the lectures.

IF the voice or ppt does not show up, wait a moment and click on the link on the upper right hand corner of the Wimba screen marked archive start. I have had to do that two times to get the ppt to show. BUT be patient. If there are a lot of people on the server it takes time to load and run. Pushing the link button ten times does not help you.

I will be out of town to attend the American Society for Biochemistry and Molecular Bio meeting April 17 - 22. For those missed days, go to the SAC and finish the assignment as decribed on your sylabus and watch the TWO identified lectures linked below:

Remember - if you are using the old version of the text book you MUST get hold of the new version for these last three sectioins, Integration of metabolism is found on chapter 22 and signal transduction and cancer are chapter 13 in the third edition of Voet Voet and Pratt. YOU MUST READ the book. ALL of this material will likely be on the test, not just the notes or the lecture recordings.

If you wish additional book chapters (from another textbook) have been linked at the bottom of your webpage. Older lecture recordings are also found there but are essentially the same as what are shown in the Wimba files above.

Good luck, stay dry, hope the sewer in my basement doesn't back up a third time! Dr Provost

Seminars-    You are required to attend two seminars this semester.  Each seminar/talk will be worth 5 points.  To get the points you must attend and submit a short synopsis of the talk with a review of the main point of the talk.  (10 total points).  See the class web site for the turn-in sheet.  Each assignment is due three calendar days after the talk.  Late reports will be docked 50%

-    Extra Credit Seminars - There will be several opportunities to go to and write up a seminar/biochemical related topic for extra credit.  SEE ABOVE FOR ANNOUNCEMENTS OF THE SEMINARS.  Each event will be worth three points for a total of 21 maximum points accumulated throughout the semester. 

• I will not review these until the end of the semester.
• It is your responsibility to keep up on what you’ve turned in.
• Each assignment is due three calendar days after the talk.
• The seminar report MUST be typed for credit.
• Late reports will be docked 50%

You will write a written report of one of the Journal of Biological Chemistry papers linked above.  I will have a review paper to support each of the articles.  Your report will be typed only.  No other form will be accepted.  Your report will be two to three pages long.

Write the report as if you were going to teach another biochemistry student.  There needs to sufficient details as to explain the mechansim / hypotyhesis and experiements described in the paper.  Your paper will have an introduction, a review of the experiements, what was done, how the experiemt was conducted and the results of the experiment and in the conclusion what the data meant as well as a larger picture of the impact of the data.  Find and discuss the hypothesis that drove the experiments and explain if the authors supported the hypothesis or not.

Each of you are responsible for writting your own paper - I highly suggest you do not work in teams so that I do not find similar papers.

You will need to look at other journal articles to help you understand the papers.